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The open reading frames (ORF)5 represents approximately 4% of the porcine reproductive and respiratory syndrome virus (PRRSV)-2 genome (whole-PRRSV) and is often determined by the Sanger technique, which rarely detects >1 PRRSV strain if present in the sample.
To clarify the genetic diversity of the porcine reproductive and respiratory syndrome virus (PRRSV) in Japan in recent years, we determined the nucleotide sequence of open reading frame 5 of 2482 PRRSV sequences obtained from samples collected from pigs between January 2018 and December 2020.
Family oral fluids (FOFs) are an aggregate sample type shown to be a cost-efficient and convenient option for determining the porcine reproductive and respiratory syndrome virus (PRRSV) status of weaning age pigs.
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Our objective was to evaluate whether porcine reproductive and respiratory syndrome virus (PRRSV) vaccination improved mortality and morbidity following experimental infection with a PRRSV restriction fragment length polymorphism 1-7-4. Results indicated that mortality and morbidity were significantly lower for vaccinated pigs as compared to unvaccinated pigs (P < .001).